Mozuku, a noodle-like seaweed, CladosiphonokamuranusTokida for its scientific name, is mainly harvested in Okinawa prefecture composed of a series of islands located in the most southern
part of Japan.
About 95% mozuku are harvested in this prefecture. Our Fucoidan has been extracted from
Mozuku. Fucoidan is a kind of dietary fiber and also contained in other sea weeds
such as Kelp (konbu), sea lettuce, hijiki, etc. Dietary fibers are indigestible in enterogastric tract so that it is excreted in feces. While it goes through enteric tract,
however, lymphatic system consisted of lymphatic tracts and lymph nodes
densely surrounding enteric tract may perceive it as foreign substance
so that it may enhance immune system to break down cancerous cells made
1. Power of fucoidan
In early 1988 a researcher announced that fucoidan contained in brown sea weeds had a power to perish cancerous cells. Also
other researchers announced following other effects of fucoidan;
1) anti coagulating effect of blood
2) resisting the outbreak of cancerous cells
3) resisting viruses
4) suppressing allergy
5) adjusting enterogastric tract
6) lowering blood cholesterol
7) anti-oxidant effect
8) anti-inflammatory effect in the skin and so on
2. Main components of mozuku and chemical compositions of fucoidan
So then what will be fucoidan and mozuku? Some foods are slippery or mucous in its nature. For instance, we can
raise okra, fermented soybean called as natto, egg white, etc. Such mucous naturer is said to be due to mucoproteins. Also kelp and mozuku have slippery nature. This is due to a polysaccharide called arginte.
Main component of mozuku is a series of dietary fibers such as fucoidan, uronate, arginate, and fuco-okigosaccharides. Sulfate residues bind to some sugars. Also there are some organic acids
Among these fucoidan is a polymer of heterosaccharide composed of many sugars such as L-fuose, d-galactose, D-glucose, D-mannose, D-wylose, and D-glucronic acid, to some of which many molecules of sulfate are binding. Fucoidan
is also called fucoidin or fucan. It is contained in many brown algae such as kelp, but mozuku contains it about 5 to 56 times more than kelp.
3. Mechanism of power of fucoidan
1) Increasing effective enteric flora and decreasing ineffective ones
As a rrole of fucoidan, it is known that it has a power to increase Bifidobacteriumbifudus known as an effective flora. Its main food is lactose which is found in
cow’s milk or human milk. In the baby’s colon the effective flora such
as Bifidobacteriumbufudus occupy about 90% of all flora, but it decreases as ages go on to about 10% at age of 70s. On
the other hand,, Clostridium perfringens (Clostridium welchii) as an ineffective flora is known to cause food poisoning. It is found
not only in soils, but also in the colon of animals and man. Ineffective
flora may produce poisonous or cancerous substances so that such flora
should be excluded from our colon. Ineffective flora may fasten againg because it may deteriorate immune system.
If there are favorable flora, it may reject ineffective flora so that it
is natural that effective flora should be increased more.
2) Why Helicobacter pylori is so fearful?
It is said that about 70% of Japanese are infected with Helicobacter pylori,
when they become 40 years old or more. This bacterium lives maninly in very mucous gastric membrane. It is also known that it may cause stomach
cancer. Gastritis so called so far is also known to be caused by this bacterium,
and it is now clear that it is related with stomach ulcer, duodenum ulcer,
stomach cancer, lymphatic tumor, etc.
In early 1989, professor Matsuda of Shimane university reported that mozuku had a bacterididal power effectively against O-157, enterohaemorrbagic E. Coli.
3) The power starts with contact Bactericidal power and apoptosis effect.
Professor Taguchi of Mie university reported that fucoidan from mozuku had not only bactericidal power but also perishing power of tumor cells.
When he put Escherichia coli or tumor cells on a Petri-dish and added a
fucoidan solution, he observed that power of fucoidan as described above. Such power to perish tumor cells is known as apoptosis,
a phenomenon of self-extinction of tumor cells. For instance, when a tadpole
grows and turns to be frog, its tail also spontaneously disappear. Such
phenomena are also known as apoptosis. This means that power of fucoidan starts with its direct contact with bacteria or tumor cells.
In fact fucoidan may have such direct effect in our body. Our digestive tracts are covered
of mucous membrane and protected by it. Mucous membrane facilitates food
stuff to move smoothly. If membrane is damaged by some cause to become
stomach or duodenum ulcer, fucoidan in its presence may cover the damaged part and protect it, and eventually
4) Transporter of cholesterol
Cholesterol is also made in liver and some of its pass through bile tract
and enter into digestive tract. Some are absorbed into intestine and come back to
liver. This is known as a phenomenon of enterohepatic circulation.
Dietary fiber has a power to reduce blood cholesterol level, since it transports
cholesterol excreted from gall into digestive tract and excretes it in
feces. Fucoidan is a dietary fiber as described before, so that it may
transport cholesterol as other dietary fibers do.
5) Activating effective flora and extinguishing harmful flora
It is said that about 300 ato 400 kinds of flora live in our large intestine, colon. That means both
effective and harmful flora coexist in it.
If fucoidan of mozuku excretes toxides produced from harmful flora, it may cleanse out body. For instance, if
you break wind with nasty smell, it may suggest that there are so many
harmful floras in your colon.
This is a case happened to my friend. He had a feeling of stomach ulcer, and his breaking wind was so stinking.
He was suffering from diarrhea so as to go toilet 4 to 5 times even in
the morning. He was told to drink fucoidan solution. Soon after that, his excretions became once or twice in a day.
And moreover he felt his stomarch became good and his excretes did not stink so much.
One more case happened to a man. His wife used to buy fucoidan solution every month for her husband. She said to me, “My husband broke
stinking wind because he had a problem in his stomach. After surgical operation,
he started to drink fucoidan solution. So soon his breaking wind did not stink so much.” Tjhis may suggest that fucoidan might exclude harmful flora with his excretes that used to cause stinking
6) Possibility of occurrence of enzyme to break fucoidan in our body
Fucoidan is a foreign substance to our body. When it enters into intestine,
it may be cousidered that our body cells may perceive it as a foreign substance, and our immune
system would highly react to it so to produce immune cells or substances,
that are the self-defensive army to protect our body. Therefore it would
be suggested that fucoidan can enhance our immune system.
4. Other effects of mozukufucoidan
Fucoidan has also other effects such as anti-tumor, prevention of coagulating
blood, adjusting intestinal disorders, and so on. Here are raised such
effects in detail to some extent.
1) Allelopathy effect
As a test mozuku in a container of sea water strongly suppressed the growth of other algae.
Such suppressive effect is called “allelopathy”. Here is a case happened to two men. They were suffering from lung cancer
and drank fucoidan solution so that their body weight increased and they got healthier.
2) Preventing effect of ulcer
Stomach is covered with mucous membrane. Mucous substance is generally
called mucoprotein, a kind of sugar-protein. “Muco” means mucous. Fucoidan is a muco-polysaccharide. So focoidan might protect stomach membrane with its mucous nature.
3) Preventing effect of blood coagulation
As a factor to prevent blood coagulation, it is known that there is a substance
called heparin in our body, a product of mucopolysaccharide produced in liver. Chemically I contains sulfate residues in itself as fucoidan does. So fucoidan also has a preventing effectof blood coagulation.
4) Anti-viral effect
It is reported that fucoidan has an effect against PRVD virus of tiger prawn and HIV virus that is
known as AIDS virus.
5) Anti-allergy effect
It is said that mozuku has an anti-allergy effect. We will raise an example of atopic dermatitis, an allergic illness; A chief doctor of a clinic in Okinawa city said that when he sprayed concentrated fucoidan solution to some patients with atopic dermatitis or dry skin for a test for few days, the itch was gone. Since
then at this clinic, he uses that concentrated solution and grains made
of the powder for treatment.
A woman who bought mozuku extract told as follows; “My son, a junior high school student, had acne
on his face and it suppurated. He used medicinal ointment on it but it
did not work effectively. I let him drink mozuku extract and also he applied it on his face. So it worked amazingly. Unbelievable”
6) Adjusting intestine disorders
As described before, fucoidan is a kind of dietary fiber. The mozuku powder contains 34.4g dietary fiber per 100g. so that it has an adjusting effect of intestine disorders.
It is a case happened to my friend’s wife. When I visited a friend of mine,
I found her face was not glossy. So I was afraid to ask her, and she replied
that she was suffering from constipation for last few years.
Then I suggested her to drink the mozuku extract as for a test, and I gave her two two bottles of it and said to keep drinking for a week. Few days later, they
visited me and she smiled and said, “It come out, it come out.”
7) Lowering effect of blood cholesterol
It is said that dietary fiber in mozuku could catch cholesterol in colon and excrete it in feces. It might be
said that as effect of dietary fiber fucoidan could lower blood cholesterol level.
8) Anti-oxidation effect
Our body needs oxygen to live. Air contains oxygen by about 20% and nitrogen
by 79%. The rests of 1% are consisted of helium and argon, and small aount of carton diwxide, etc. Oxygen is essential substance for us to live. However, sometimes
it is activated so harmful with its so reactive property. This oxygen is called radical oxygen. It must be
lessen in our body. The substances to lessen it are called “anti-oxidants.”
Vitamine C, vitamine E or carrotine, etc. are included in it. Fuciodan also has an anti-oxidation effect.
9) Preventing effect of dermatitis
We can not live without sun beam. Sun gives us not only energy but also it activates vitamin D taken into our body from the
outside. In sun beam ultra violet rays and infrared ray are included. Some
ultra violet ray activates vitamin D and infrared ray gives heat. But when
exposed with both rays too much, it causes inflammation on the skin.
It is lucky, however, that as a result of experiment fucoidan solution was known to prevent this inflammation.
When fucoidan solution is anointed on the skin, it is sticky first, but after a few
minutes it becomes very smooth, and you may feel good. This may mean that
slippery nature of fucodian really protects our skin.
As such mentioned above, fucoidan has so many tremendous effects. But you have to be aware that most of
the effects so far mentioned are the results of in vitro experiments. The
clinical cases shown here come from the experiences of the suffering people.
Therefore we have to wait so many clinical results.
As described above, we have been seeing so many cases that after drinking
fucoidan solution, stomach ulcer was really cured, or stink of feces was gone away.
This may show that fucoidan worked so surely and effectively in our body by some ways. We have to
permit wonderful power of fucoidan.